34089

Fosfomycin sodium

VETRANAL^®, analytical standard

• Sinónimos: Phosphomycin disodium salt, (−)-(1R,2S)-(1,2-Epoxypropyl)phosphonic acid, Fosfomycin, Phosphonomycin
• Fórmula empírica (notación de Hill): C₃H₅Na₂O₄P
• Peso molecular: 182.02
• Beilstein: 4604425
• Número CE: 247-409-2
• Número MDL: MFCD22741288
• Código UNSPSC: 41116107
• ID de la sustancia en PubChem: 329754806
• NACRES: NA.24

Propiedades

• grado: analytical standard
• Nivel de calidad: 100
• Línea del producto: VETRANAL^®
• caducidad: limited shelf life, expiry date on the label
• técnicas: HPLC: suitable; gas chromatography (GC): suitable
• aplicaciones: clinical testing
• formato: neat
• temp. de almacenamiento: 2-8°C
• cadena SMILES: [Na+].[Na+].C[C@@H]1O[C@@H]1P([O-])([O-])=O
• InChI: 1S/C3H7O4P.2Na/c1-2-3(7-2)8(4,5)6;;/h2-3H,1H3,(H2,4,5,6);;/q;2*+1/p-2/t2-,3+;;/m0../s1
• Clave InChI: QZIQJIKUVJMTDG-JSTPYPERSA-L

Descripción

Aplicación

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Acciones bioquímicas o fisiológicas

Antibiotic that concentrates in kidney and bladder; reduces nephrotoxicity and ototoxicity of platinum-containing anti-tumor agents. Fosfomycin is a phosphoenolpyruvate analog that irreversibly inhibits UDP-GlcNAc enolpyruvyl tranferase (MurA), an enzyme involved in bacterial cell wall biosynthesis. As a result, the production of N-acetylmuramic acid, an essential element of the peptidoglycan cell wall, is inhibited.

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Información legal

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)