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00370580

Ginsenoside Rg1

primary reference standard

Sinónimos:

(3β,6α,12β)-3,12-Dihydroxydammar-24-ene-6,20-diyl bis-β-D-glucopyranoside

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About This Item

Fórmula empírica (notación de Hill):
C42H72O14
Número de CAS:
22427-39-0
Peso molecular:
801.01
Número CE:
244-989-9
Número MDL:
MFCD00210293
Código UNSPSC:
85151701
ID de la sustancia en PubChem:
329747051
NACRES:
NA.24

grado

primary reference standard

caducidad

limited shelf life, expiry date on the label

fabricante / nombre comercial

HWI

técnicas

HPLC: suitable
gas chromatography (GC): suitable

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

cadena SMILES

C[C@]12[C@@](C[C@H]([C@@]3([H])[C@]2(CC[C@]3([H])[C@@](CCC=C(C)C)(C)O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO)C)O)([H])[C@@]5([C@@](C(C)([C@H](CC5)O)C)([H])[C@H](C1)O[C@@H]6O[C@@H]([C@H]([C@@H]([C@H]6O)O)O)CO)C

InChI

1S/C42H72O14/c1-20(2)10-9-13-42(8,56-37-34(52)32(50)30(48)25(19-44)55-37)21-11-15-40(6)28(21)22(45)16-26-39(5)14-12-27(46)38(3,4)35(39)23(17-41(26,40)7)53-36-33(51)31(49)29(47)24(18-43)54-36/h10,21-37,43-52H,9,11-19H2,1-8H3/t21-,22+,23-,24+,25+,26+,27-,28-,29+,30+,31-,32-,33+,34+,35-,36+,37-,39+,40+,41+,42-/m0/s1

Clave InChI

YURJSTAIMNSZAE-HHNZYBFYSA-N

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Descripción general

Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

Aplicación

Reference standard in the analysis of herbal medicinal products.

Otras notas

This compound is commonly found in plants of the genus: panax

Pictogramas

Exclamation mark
GHS07

Palabra de señalización

Warning

Frases de peligro

H302

Clasificaciones de peligro

Acute Tox. 4 Oral

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Choose from one of the most recent versions:

Certificados de análisis (COA)

Lot/Batch Number
HWI03094-1
HWI03094
HWI02086-2
HWI02086-1
HWI02086

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Wei Li et al.
Brain research bulletin, 88(5), 501-506 (2012-05-24)
Excessive accumulation of amyloid-β (Aβ) has been proposed as a pivotal event in Alzheimer's disease (AD) pathogenesis. Possible mechanisms underlying Aβ-induced neurotoxicity include inflammation and apoptosis. Here, the protective effect of ginsenoside Rg1 (GRg1) on neuronal damage was examined in
QianKun Quan et al.
PloS one, 8(3), e59155-e59155 (2013-03-23)
The present study was designed to examine the effects of ginsenoside Rg1 on expression of peroxisome proliferator-activated receptor γ (PPARγ) and insulin-degrading enzyme (IDE) in the hippocampus of rat model of Alzheimer's disease (AD) to determine how ginsenoside Rg1 (Rg1)
Wei Li et al.
Life sciences, 91(15-16), 809-815 (2012-09-18)
In the present study we aimed to investigate the neuroprotective effect of ginsenoside Rg1 (GRg1) on neuronal damage examined in an adopted in vitro inflammatory neurodegeneration model and the involvement of p38 MAPK signal pathway. The supernatant from Aβ(1-40)-stimulated THP-1
Jiaying Wu et al.
Neurochemistry international, 62(1), 92-102 (2012-10-16)
Ginsenoside Rg1, a steroidal saponin of high abundance in ginseng, possesses the neuroprotective effects. In this study, we tried to explore the effect of Rg1 on promoting differentiation of mouse embryonic stem (ES) cells towards the neuronal lineage and its
Y Takino
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 114(8), 550-564 (1994-08-01)
The pharmacodynamics of ginsenoside-Rg1 (Rg1), -Rb1 (Rb1) and -Rb2 (Rb2) in rats were studied. In these studies, obvious differences were found in their pharmacodynamics. That is, Rg1 was easily hydrated to the same prospogenins in both rat stomach and 0.1
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