8.20128

Saccharin

for synthesis

• Sinónimos: Saccharin
• Fórmula empírica (notación de Hill): C₇H₅NO₃S
• Número de CAS: 81-07-2
• Peso molecular: 183.18
• Número MDL: MFCD00005866
• Código UNSPSC: 12352115
• Número índice de la CE: 201-321-0
• NACRES: NA.22

Propiedades

• Nivel de calidad: 200
• Análisis: ≥98.0% (acidimetric)
• formulario: crystals
• mp: 228-230 °C
• temp. de almacenamiento: 2-30°C
• InChI: 1S/C7H5NO3S/c9-7-5-3-1-2-4-6(5)12(10,11)8-7/h1-4H,(H,8,9)
• Clave InChI: CVHZOJJKTDOEJC-UHFFFAOYSA-N

Descripción

Aplicación

• Gabapentin-saccharin co-crystals with enhanced physicochemical properties and in vivo absorption formulated as oro-dispersible tablets.: This study presents the formulation of gabapentin-saccharin co-crystals, demonstrating improved solubility and absorption, beneficial for pharmaceutical applications (Soliman et al., 2020, doi: 10.1080/10837450.2019.1687521).


• Improving the solubility, dissolution, and bioavailability of Ibrutinib by preparing it in a coamorphous state with saccharin.: The research focuses on enhancing the bioavailability of Ibrutinib through coamorphous preparation with saccharin, which is significant for cancer treatment (Shi et al., 2019, doi: 10.1016/j.xphs.2019.04.031).

Nota de análisis

Assay (acidimetric): ≥ 98.0 %
Melting range (lower value): ≥ 226 °C
Melting range (upper value): ≤ 230 °C
Identity (IR): passes test

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable