07-1497
Anti-cAMP Antibody
serum, from rabbit
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About This Item
Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Productos recomendados
origen biológico
rabbit
Nivel de calidad
forma del anticuerpo
serum
tipo de anticuerpo
primary antibodies
clon
polyclonal
reactividad de especies
rat
reactividad de especies (predicha por homología)
all
técnicas
immunohistochemistry: suitable (paraffin)
Condiciones de envío
wet ice
modificación del objetivo postraduccional
unmodified
Descripción general
Cyclic adenosine monophosphate or cAMP is an intracellular by-product of ATP by adenylene cyclase when G-protein Coupled Receptors (GPCR) bind various ligands on the cell surface. Cyclic AMP acts as a second messenger for signal transduction across the cell membrane and is a part of kinase activation. It regulates the effects of glucagon and adrenaline along with the movement of calcium ions through ion channels. Since it is affected directly by GPCR activation, cAMP is studied as a means to monitor GPCR in the discovery of therapeutic drugs.
Especificidad
Specific for cAMP with no cross reaction to other nucleotides at concentrations to 1 mM. Reactive with cAMP fixed in tissues or acetylated cAMP. Not reactive with free, non-acetylated, cAMP in RIA or EIA assays.
Inmunógeno
2′O-succinyl cyclic AMP conjugated to BSA
Aplicación
Anti-cAMP Antibody detects level of cAMP & has been published & validated for use in IH(P).
Research Category
Signaling
Signaling
Research Sub Category
GPCR, cAMP/cGMP & Calcium Signaling
GPCR, cAMP/cGMP & Calcium Signaling
Calidad
Evaluated by Immunohistochemistry in rat hippocampus and cerebellum tissue.
Immunohistochemistry Analysis: 1:100 dilution of this lot detected cAMP in rat hippocampus and cerebellum tissue.
Immunohistochemistry Analysis: 1:100 dilution of this lot detected cAMP in rat hippocampus and cerebellum tissue.
Ligadura / enlace
Replaces: MABN1026
Forma física
Diluted serum presented as liquid in PBS containing no preservatives.
Unpurified rabbit serum
Almacenamiento y estabilidad
Maintain at -20°C in undiluted aliquots from date of shipment. Avoid repeated freeze/thaw cycles.
Nota de análisis
Control
Rat hippocampus and cerebellum tissue
Rat hippocampus and cerebellum tissue
Cláusula de descargo de responsabilidad
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Código de clase de almacenamiento
12 - Non Combustible Liquids
Clase de riesgo para el agua (WGK)
WGK 2
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
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