Todas las fotos(2)

Documentos clave

05-435

Anti-Lck Antibody, clone 3A5

Name: Anti-Lck Antibody, clone 3A5
Brand: MM

clone 3A5, Upstate^®, from mouse

Sinónimos:

Anti-IMD22, Anti-LSK, Anti-YT16, Anti-p56lck, Anti-pp58lck

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización

Todas las fotos(2)

About This Item

Código UNSPSC:

12352203

eCl@ss:

32160702

NACRES:

NA.41

origen biológico

mouse

Nivel de calidad

100

forma del anticuerpo

purified immunoglobulin

tipo de anticuerpo

primary antibodies

clon

3A5, monoclonal

reactividad de especies

mouse, human, rat

fabricante / nombre comercial

Upstate^®

técnicas

immunoprecipitation (IP): suitable
western blot: suitable

isotipo

IgG2bκ

Nº de acceso NCBI

NM_005356

Nº de acceso UniProt

P06239

Condiciones de envío

dry ice

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... LCK(3932)

Especificidad

Recognizes Lck.

Inmunógeno

GST-fusion to residues 1-225 of murine Lck

Aplicación

Research Category
Signaling

Research Sub Category
Immunological Signaling

This Anti-Lck Antibody, clone 3A5 is validated for use in IP, WB for the detection of Lck.

Calidad

routinely evaluated by immunoblot on RIPA lysates from Jurkat cells

Descripción de destino

56 kDa

Ligadura / enlace

Replaces: 04-372

Forma física

Format: Purified

Protein A purified

Protein A purified antibody in 100uL of 10mM PBS, pH 7.4

Almacenamiento y estabilidad

Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Nota de análisis

Control
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Información legal

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

¿No encuentra el producto adecuado?

Pruebe nuestro Herramienta de selección de productos.

Código de clase de almacenamiento

12 - Non Combustible Liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Association of SRC-related kinase Lyn with the interleukin-2 receptor and its role in maintaining constitutive phosphorylation of JAK/STAT in human T-cell leukemia virus type 1-transformed T cells.

Shuh, M; Morse, BA; Heidecker, G; Derse, D

Journal of virology null

The Lck tyrosine kinase is expressed in brain neurons.

B Omri et al.

Journal of neurochemistry, 67(4), 1360-1364 (1996-10-01)

The lck gene product, p56lck, is a member of the src-related family of protein tyrosine kinases. It is known as lymphocyte specific and involved in thymocyte development and in the immune response mediated by the T cell receptor. We report

The differential expression of LCK and BAFF-receptor and their role in apoptosis in human lymphomas.

Jennifer C Paterson, Sara Tedoldi, Andrew Craxton, Margaret Jones, Martin-Leo Hansmann et al.

Haematologica null

Mutational Analysis of Glycogen Synthase Kinase 3β Protein Kinase Together with Kinome-Wide Binding and Stability Studies Suggests Context-Dependent Recognition of Kinases by the Chaperone Heat Shock Protein 90.

Jing Jin et al.

Molecular and cellular biology, 36(6), 1007-1018 (2016-01-13)

The heat shock protein 90 (HSP90) and cell division cycle 37 (CDC37) chaperones are key regulators of protein kinase folding and maturation. Recent evidence suggests that thermodynamic properties of kinases, rather than primary sequences, are recognized by the chaperones. In

T cell receptor-dependent S-acylation of ZAP-70 controls activation of T cells.

Ritika Tewari et al.

The Journal of biological chemistry, 296, 100311-100311 (2021-01-23)

ZAP-70 is a tyrosine kinase essential for T cell immune responses. Upon engagement of the T cell receptor (TCR), ZAP-70 is recruited to the specialized plasma membrane domains, becomes activated, and is released to phosphorylate its laterally segregated targets. A

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico