04-1470

Anti-OX40L (CD252) Antibody, clone RM134L

clone RM134L, from rat

• Sinónimos: Tumor necrosis factor ligand superfamily member 4, OX40 ligand, OX40L, CD252
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• origen biológico: rat
• Nivel de calidad: 100
• forma del anticuerpo: purified immunoglobulin
• tipo de anticuerpo: primary antibodies
• clon: RM134L, monoclonal
• reactividad de especies: mouse
• técnicas: flow cytometry: suitable; immunohistochemistry: suitable
• isotipo: IgG2bκ
• Nº de acceso NCBI: NP_033478
• Nº de acceso UniProt: P43488
• Condiciones de envío: wet ice
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: mouse ... Tnfsf4(22164)

Descripción

Descripción general

OX40L (Tumor necrosis factor ligand superfamily member 4; or CD252) is the endogenous ligand of the OX40 receptor. OX40 is localized on activated T-cells and propagates the immune response by promoting division and survival of T-cells, thereby increasing the population of memory CD4 and CD8 T cells produced in response to antigen detection. The OX40/OX40L may also regulate cytokine production and suppress the activity of T-regulatory cells. OX40/OX40L is therefore an important mediator of the immune response. Previous studies have suggested that OX40 signaling maybe involved in the development of autoimmune diseases.

Especificidad

This antibody recognizes the extracellular domain of OX40L.

Inmunógeno

Mouse OX40L cDNA-transfected NRK cells

Aplicación

Anti-OX40L (CD252) Antibody, clone RM134L detects level of OX40L (CD252) & has been published & validated for use in Flow Cytometry & IHC.

Immunohistochemistry Analysis: A representative lot was used by an independent laboratory in mouse lung tissue. (Hoshino, A., et al. (2003). Eur. J. Immunol. 33:861–869.)

Calidad

Evaluated by Flow Cytometry in mouse OX40L/L5178Y cells.

Flow Cytometry Analysis: 10 µg of this antibody detected OX40L in mouse OX40L/L5178Y cells.

Descripción de destino

22 kDa calculated

Forma física

Format: Purified

Nota de análisis

Control
Mouse OX40L/L5178Y cells

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable