H-110

Hydroxyitraconazole

100 μg/mL in methanol, certified reference material, Cerilliant^®

• Fórmula empírica (notación de Hill): C₃₅H₃₈Cl₂N₈O₅
• Número de CAS: 112559-91-8
• Peso molecular: 721.63
• Código UNSPSC: 41116107
• NACRES: NA.24

Propiedades

• grado: certified reference material
• Nivel de calidad: 300
• Formulario: liquid
• Características: Snap-N-Spike^®/Snap-N-Shoot^®
• envase: ampule of 1 mL
• fabricante / nombre comercial: Cerilliant^®
• concentración: 100 μg/mL in methanol
• técnicas: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• aplicaciones: clinical testing
• Formato: single component solution
• temp. de almacenamiento: −20°C
• cadena SMILES: Clc1c(ccc(c1)Cl)C3(OC(CO3)COc4ccc(cc4)N5CCN(CC5)c6ccc(cc6)N7C=NN(C7=O)C(C(O)C)C)C[n]2ncnc2
• InChI: 1S/C35H38Cl2N8O5/c1-24(25(2)46)45-34(47)44(23-40-45)29-6-4-27(5-7-29)41-13-15-42(16-14-41)28-8-10-30(11-9-28)48-18-31-19-49-35(50-31,20-43-22-38-21-39-43)32-12-3-26(36)17-33(32)37/h3-12,17,21-25,31,46H,13-16,18-20H2,1-2H3
• Clave InChI: ISJVOEOJQLKSJU-UHFFFAOYSA-N

Descripción

Descripción general

Hydroxyitraconazole is an active metabolite of itraconazole, an antifungal drug used for the treatment of fungal infections. Therapeutic drug monitoring of hydroxyitraconazole is utilized in the management of patients receiving itraconazole to ensure therapeutic levels of the drug have been achieved. This Certified Spiking Solution^® is suitable as starting material for calibrators, controls, or linearity standards for therapeutic drug monitoring or clinical and diagnostic testing of hydroxyitraconazole in patient blood, serum, or plasma samples by HPLC or LC-MS/MS.

Información legal

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Pictogramas: GHS02,GHS06,GHS08
• Palabra de señalización: Danger
• Frases de peligro: H225,H301 + H311 + H331,H370
• Consejos de prudencia: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Clasificaciones de peligro: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Órganos de actuación: Eyes
• Código de clase de almacenamiento: 3 - Flammable liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): 49.5 °F - closed cup
• Punto de inflamabilidad (°C): 9.7 °C - closed cup