900893

L-Homopropargylglycine hydrochloride

• Sinónimos: HPG
• Fórmula empírica (notación de Hill): C₆H₉NO₂ · HCl
• Número de CAS: 98891-36-2
• Peso molecular: 163.60
• Código UNSPSC: 12352209
• NACRES: NA.22

Propiedades

• formulario: powder or crystals
• disponibilidad: available only in USA
• mp: 162 °C
• temp. de almacenamiento: −20°C
• cadena SMILES: O=C(O[H])[C@@](C([H])([H])C([H])([H])C#C[H])([H])N([H])[H].Cl[H]
• InChI: 1S/C6H9NO2/c1-2-3-4-5(7)6(8)9/h1,5H,3-4,7H2,(H,8,9)
• Clave InChI: SCGJGNWMYSYORS-UHFFFAOYSA-N

Descripción

Aplicación

L-Homopropargylglycine (HPG) is an amino acid analog of methionine that contains a very small modification, specifically an alkyne moiety. This compound can be fed to cultured cells and incorporated into proteins during active protein synthesis. Detection utilizes the chemoselective ligation or “click” reaction between an azide and an alkyne or cyclooctyne. For example the alkyne-modified protein can be detected with either fluorescent azide or biotin azide. Detection sensitivity with these reagents in 1-D gels and Western blots is in the low femtomole range and compatible with downstream LC-MS/MS and MALDI-MS analysis.

Información de seguridad

• Pictogramas: GHS02
• Palabra de señalización: Danger
• Frases de peligro: H242
• Consejos de prudencia: P210 - P234 - P235 - P240 - P370 + P378 - P403
• Clasificaciones de peligro: Self-react. C
• Código de clase de almacenamiento: 5.2 - Organic peroxides and self-reacting hazardous materials
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable