790451

TCO-amine HCl salt

• Sinónimos: trans-Cyclooctene-amine hydrochloride salt, TCO-NH2, HCl salt
• Fórmula empírica (notación de Hill): C₁₂H₂₂N₂O₂ · HCl
• Peso molecular: 262.78
• Código UNSPSC: 12352116
• ID de la sustancia en PubChem: 329768216
• NACRES: NA.22

Propiedades

• formulario: solid
• idoneidad de la reacción: reaction type: click chemistry; reagent type: linker
• grupo funcional: amine
• temp. de almacenamiento: −20°C
• cadena SMILES: O=C(NCCCN)OC1CCC/C=C/CC1.[H]Cl
• InChI: 1S/C12H22N2O2.ClH/c13-9-6-10-14-12(15)16-11-7-4-2-1-3-5-8-11;/h1-2,11H,3-10,13H2,(H,14,15);1H/b2-1+;
• Clave InChI: GIYQQURLGCGUKK-TYYBGVCCSA-N

Descripción

Aplicación

Amine functionalized trans-cyclooctene derivative for incorporation of the cyclooctene moiety into carboxyl containing compounds or biomolecules via standard coupling techniques (DCC; EDC etc...). Trans-cyclooctenes are useful in strain-promoted copper-free click chemistry cycloaddition reactions with 1; 2; 4; 5-tetrazines. This cyclooctene will react with tetrazine functionalized compounds or biomolecules without the need for a catalyst to result in a stable covalent linkage. The 4+2 inverse electron demand Diels-Alder cycloaddition between trans-cyclooctene and tetrazines is the fastest biologically compatible ligation technology reported and has had many applications in biological labeling and imaging.

Información de seguridad

• Pictogramas: GHS07
• Palabra de señalización: Warning
• Frases de peligro: H302
• Clasificaciones de peligro: Acute Tox. 4 Oral
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable