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Sigma-Aldrich

Poly(ethylene glycol) methyl ether thiol

average MN 6,000, chemical modification reagent thiol reactive, methoxy, thiol

Sinónimos:

Polyethylene glycol, Methoxy PEG thiol, Methoxypolyethylene glycol thiol, PEG thiol, mPEG thiol

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About This Item

Fórmula lineal:
CH3O(CH2CH2O)nCH2CH2SH
Código UNSPSC:
12162002
NACRES:
NA.23

product name

Poly(ethylene glycol) methyl ether thiol, average Mn 6,000

formulario

solid

mol peso

average Mn 6,000

idoneidad de la reacción

reagent type: chemical modification reagent
reactivity: thiol reactive

mp

56-61 °C

Mw/Mn

≤1.2

Ω-final

thiol

α-final

methoxy

arquitectura del polímero

shape: linear
functionality: monofunctional

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

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Descripción general

Poly(ethylene glycol) methyl ether thiol (mPEGthiol) is a thiol-terminated biocompatible polymer widely used in the surfacefunctionalization of gold nanoparticles. Thiol moieties bind with high affinityto gold surfaces by forming a self-assembled monolayer (SAM) through thecovalent thiolate–metal bond. mPEG thiol-coated Au nanoparticles findapplication in the fields of biosensors and drug delivery systems.

Aplicación

Poly(ethylene glycol) methyl ether thiol-coated Au nanoparticles can be used for the determination of melamine T. by an optical method. It can also be used to fabricate switchable super-wetting membranes foroil/water separation.

Pictogramas

Exclamation mark
GHS07

Palabra de señalización

Warning

Frases de peligro

H315,H319,H335

Clasificaciones de peligro

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Órganos de actuación

Respiratory system

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Certificados de análisis (COA)

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Artículos

Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Versatile Cell Culture Scaffolds via Bio-orthogonal Click Reactions

Devising biomaterial scaffolds that are capable of recapitulating critical aspects of the complex extracellular nature of living tissues in a threedimensional (3D) fashion is a challenging requirement in the field of tissue engineering and regenerative medicine.

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