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Merck

UBR1

ubiquitin protein ligase E3 component n-recognin 1

Sinónimos:
JBS
Especie:
Human UBR1 (197131), Mouse Ubr1 (22222), Rat Ubr1 (499877), Zebrafish ubr1 (568531), Horse UBR1 (100056497), domestic cat UBR1 (101081553), dog UBR1 (487521), chicken UBR1 (423242), cow UBR1 (522464), sheep UBR1 (101119567) ...Más
ID UniProtKB:
Q8IWV7, O60708, O75492, Q14D45, Q68DN9, Q8IWY6, Q96JY4
ID del gen:
  • Human(197131) Summary: The N-end rule pathway is one proteolytic pathway of the ubiquitin system. The recognition component of this pathway, encoded by this gene, binds to a destabilizing N-terminal residue of a substrate protein and participates in the formation of a substrate-linked multiubiquitin chain. This leads to the eventual degradation of the substrate protein. The protein described in this record has a RING-type zinc finger and a UBR-type zinc finger. Mutations in this gene have been associated with Johanson-Blizzard syndrome. [provided by RefSeq, Jul 2008]
  • Mouse(22222) ubiquitin protein ligase E3 component n-recognin 1
  • Rat(499877) ubiquitin protein ligase E3 component n-recognin 1
  • Zebrafish(568531) ubiquitin protein ligase E3 component n-recognin 1
  • Horse(100056497) ubiquitin protein ligase E3 component n-recognin 1
  • domestic cat(101081553) ubiquitin protein ligase E3 component n-recognin 1
  • dog(487521) ubiquitin protein ligase E3 component n-recognin 1
  • chicken(423242) ubiquitin protein ligase E3 component n-recognin 1
  • cow(522464) ubiquitin protein ligase E3 component n-recognin 1
  • sheep(101119567) ubiquitin protein ligase E3 component n-recognin 1
  • Domestic Rabbit(100338337) ubiquitin protein ligase E3 component n-recognin 1
  • naked mole-rat(101719904) ubiquitin protein ligase E3 component n-recognin 1
  • domestic guinea pig(100715624) ubiquitin protein ligase E3 component n-recognin 1

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
HPA038838
Anti-UBR1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
HPA038839
Anti-UBR1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
SAB1408967
Monoclonal Anti-UBR1 antibody produced in mouse, clone 4G7, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
immunofluorescence
HPA046727
Anti-Ubr1 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
MABS1180
Anti-E3 ubiquitin-protein ligase UBR1 Antibody, clone 6H9.1, clone 6H9.1, from mouse,
Reactividad de especies
human, rat
Aplicación
immunohistochemistry
western blot

esiRNA

Referencia del producto
Descripción
Especie
EHU053301
MISSION® esiRNA, targeting human UBR1,
Especie
human