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Merck

TLR6

toll-like receptor 6

Sinónimos:
CD286
Especie:
ID UniProtKB:
ID del gen:
  • Human(10333) Summary: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor functionally interacts with toll-like receptor 2 to mediate cellular response to bacterial lipoproteins. A Ser249Pro polymorphism in the extracellular domain of the encoded protein may be associated with an increased of asthma is some populations.[provided by RefSeq, Jan 2011]
  • Mouse(21899) toll-like receptor 6
  • Rat(305353) toll-like receptor 6
  • domestic cat(493662) toll-like receptor 6
  • Horse(100064554) toll-like receptor 6
  • dog(100684818) toll-like receptor 6
  • domestic guinea pig(100733137) toll-like receptor 6
  • naked mole-rat(101718313) toll-like receptor 6
  • Domestic Rabbit(100353753) toll-like receptor 6
  • cow(407237) toll-like receptor 6
  • Goat(100860932) toll-like receptor 6
  • sheep(554257) toll-like receptor 6

Custom & Knockdown Gene Products

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  • Custom Gene Products

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-TLR6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
Anti-TLR6 (ab1) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human, mouse
Aplicación
ELISA
immunocytochemistry

western blot
Anti-TLR6 (ab2) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
immunohistochemistry

western blot
ANTI-TLR6 antibody produced in mouse, clone 1C12, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
ANTI-TLR6 antibody produced in mouse, clone 3D11, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human TLR6,
Especie
human
MISSION® esiRNA, targeting human TLR6 (2),
Especie
human
MISSION® esiRNA, targeting mouse Tlr6,
Especie
mouse