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Merck

TIMP2

TIMP metallopeptidase inhibitor 2

Sinónimos:
CSC-21K, DDC8
Especie:
Human TIMP2 (7077), Mouse Timp2 (21858), Rat Timp2 (29543), chicken TIMP2 (374178), dog TIMP2 (403633), Horse TIMP2 (100034134), domestic cat TIMP2 (101083125), domestic guinea pig Timp2 (100135629), naked mole-rat Timp2 (101707659), Domestic Rabbit TIMP2 (100008689) ...Más
ID UniProtKB:
P16035, Q16121, Q93006, Q9UDF7
ID del gen:
  • Human(7077) Summary: This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. [provided by RefSeq, Jul 2008]
  • Mouse(21858) tissue inhibitor of metalloproteinase 2
  • Rat(29543) TIMP metallopeptidase inhibitor 2
  • chicken(374178) TIMP metallopeptidase inhibitor 2
  • dog(403633) TIMP metallopeptidase inhibitor 2
  • Horse(100034134) TIMP metallopeptidase inhibitor 2
  • domestic cat(101083125) TIMP metallopeptidase inhibitor 2
  • domestic guinea pig(100135629) tissue inhibitor of metalloproteinase 2
  • naked mole-rat(101707659) TIMP metallopeptidase inhibitor 2
  • Domestic Rabbit(100008689) TIMP metallopeptidase inhibitor 2
  • cow(282093) TIMP metallopeptidase inhibitor 2
  • sheep(100217406) TIMP metallopeptidase inhibitor 2

Custom & Knockdown Gene Products

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ELISA

Referencia del producto
Descripción
Especie
RAB0472
Human TIMP-2 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Especie
human
RAB1156
Rat TIMP-2 ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Especie
rat
RAB0879
Porcine TIMP2 / Tissue Inhibitor of Metalloproteinase-2 ELISA Kit, ,
Especie
RAB0579
Canine TIMP2 / Metalloproteinase Inhibitor 2 ELISA Kit, ,
Especie
dog
RAB0473
Mouse TIMP-2 ELISA Kit, for serum, plasma and cell culture supernatant,
Especie
mouse

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
SAB4502972
Anti-TIMP2 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunofluorescence
western blot
MAB3310
Anti-TIMP-2 Antibody, clone 67-4H11, clone 67-4H11, Chemicon®, from mouse,
Reactividad de especies
bovine, goat, guinea pig, human, mouse, rabbit, rat
Aplicación
ELISA
immunohistochemistry
western blot
SAB4200814
Anti-TIMP2 antibody, Mouse monoclonal, clone TM8, purified from hybridoma cell culture,
Reactividad de especies
human
Aplicación
immunofluorescence
western blot
SAB5702264
Anti-TIMP2 Antibody, clone 8R5Q2, Rabbit Monoclonal, ,
Reactividad de especies
african green monkey, human, mouse, rat
Aplicación
western blot
SAB5700746
Anti-TIMP2 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunofluorescence
western blot

Proteins

Referencia del producto
Descripción
Especie
SRP3174
TIMP-2 human, recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
EHU017331
MISSION® esiRNA, targeting human TIMP2,
Especie
human
EMU090361
MISSION® esiRNA, targeting mouse Timp2,
Especie
mouse