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Merck

SOCS3

suppressor of cytokine signaling 3

Sinónimos:
ATOD4, CIS3, Cish3, SOCS-3, SSI-3, SSI3
Especie:
ID UniProtKB:
ID del gen:
  • Human(9021) Summary: This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development. [provided by RefSeq, Jul 2008]
  • Mouse(12702) suppressor of cytokine signaling 3
  • Rat(89829) suppressor of cytokine signaling 3
  • chicken(395299) suppressor of cytokine signaling 3
  • Horse(100050730) suppressor of cytokine signaling 3
  • domestic cat(101081846) suppressor of cytokine signaling 3
  • dog(442949) suppressor of cytokine signaling 3
  • cow(282081) suppressor of cytokine signaling 3
  • sheep(100294595) suppressor of cytokine signaling 3
  • domestic guinea pig(100725088) suppressor of cytokine signaling 3
  • naked mole-rat(101704157) suppressor of cytokine signaling 3

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-SOCS3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
Monoclonal Anti-SOCS3 antibody produced in mouse, clone 2E5, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
Anti-SOCS3 Antibody, clone 1B2, clone 1B2, Upstate®, from mouse,
Reactividad de especies
human, mouse
Aplicación
western blot
Monoclonal Anti-SOCS3 antibody produced in mouse, clone 1E4, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
immunofluorescence
Monoclonal Anti-SOCS3 antibody produced in mouse, clone SO1,
Reactividad de especies
human
Aplicación
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human SOCS3,
Especie
human
MISSION® esiRNA, targeting mouse Socs3,
Especie
mouse