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Merck

PTGS2

prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

Sinónimos:
COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2
Especie:
ID UniProtKB:
ID del gen:
  • Human(5743) Summary: Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq, Feb 2009]
  • Mouse(19225) prostaglandin-endoperoxide synthase 2
  • Rat(29527) prostaglandin-endoperoxide synthase 2
  • cow(282023) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • sheep(443460) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • Goat(100860905) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • naked mole-rat(101704771) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • Domestic Rabbit(100009248) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • domestic guinea pig(100135607) prostaglandin-endoperoxide synthase 2
  • chicken(396451) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • Horse(791253) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • domestic cat(100126581) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • dog(442942) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

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ELISA

Referencia del producto
Descripción
Especie
Human COX-2 ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Especie
human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
COX-2 (SP21) Rabbit Monoclonal Antibody, ,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-COX2/PTGS2 Antibody, clone 2V7G8, Rabbit Monoclonal, ,
Reactividad de especies
mouse
Aplicación
immunohistochemistry
western blot
Anti-COX2 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human
Aplicación
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-Cox2 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunofluorescence
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-COX2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry

Small Molecule - Blocker

Referencia del producto
Descripción
Especie
N-p-Tosyl-L-phenylalanine chloromethyl ketone, ≥97% (TLC), powder,
Especie
human

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
Carprofen, ≥97% (HPLC),
Especie
human
Aceclofenac, ≥98% (HPLC),
Especie
human
Celecoxib, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Carprofen, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Etoricoxib, VETRANAL®, analytical standard,
Especie
human

Proteins

Referencia del producto
Descripción
Especie
Cyclooxygenase 2 human, ≥70% (SDS-PAGE), recombinant, expressed in insect cells, aqueous solution, ≥8000 units/mg protein,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Ptgs2,
Especie
mouse
MISSION® esiRNA, targeting human PTGS2,
Especie
human