PGC
progastricsin (pepsinogen C)
Sinónimos:
PEPC, PGII
Especie:
Human PGC (5225), Mouse Pgc (109820), Rat Pgc (24864), cow PGC (514502), sheep PGC (101106633), naked mole-rat Pgc (101713573), Domestic Rabbit PGC (100009323), domestic guinea pig Pgc (100135598), fruit fly pgc (5740599), domestic cat PGC (101100053) ...Más
ID UniProtKB:
ID del gen:
- Human(5225) Summary: This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Oct 2009]
- Mouse(109820) progastricsin (pepsinogen C)
- Rat(24864) progastricsin (pepsinogen C)
- cow(514502) progastricsin (pepsinogen C)
- sheep(101106633) progastricsin (pepsinogen C)
- naked mole-rat(101713573) progastricsin (pepsinogen C)
- Domestic Rabbit(100009323) progastricsin (pepsinogen C)
- domestic guinea pig(100135598) progastricsin (pepsinogen C)
- fruit fly(5740599) polar granule component
- domestic cat(101100053) progastricsin (pepsinogen C)
- dog(609052) progastricsin (pepsinogen C)
- chicken(395690) progastricsin (pepsinogen C)
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-PGC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
western blot
Anti-PGC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
western blot
Anti-PGC antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution,
Reactividad de especies
human
Aplicación
western blot
Anti-PGC antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
western blot
esiRNA
Referencia del producto
Descripción
Especie