PEX19
peroxisomal biogenesis factor 19
Sinónimos:
D1S2223E, HK33, PBD12A, PMP1, PMPI, PXF, PXMP1
Especie:
Human PEX19 (5824), Mouse Pex19 (19298), Rat Pex19 (289233), domestic guinea pig Pex19 (100730897), naked mole-rat Pex19 (101718390), cow PEX19 (521522), sheep PEX19 (101119432), fruit fly Pex19 (34630), dog PEX19 (478972), Zebrafish pex19 (324778)
ID UniProtKB:
ID del gen:
- Human(5824) Summary: This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010]
- Mouse(19298) peroxisomal biogenesis factor 19
- Rat(289233) peroxisomal biogenesis factor 19
- domestic guinea pig(100730897) peroxisomal biogenesis factor 19
- naked mole-rat(101718390) peroxisomal biogenesis factor 19
- cow(521522) peroxisomal biogenesis factor 19
- sheep(101119432) peroxisomal biogenesis factor 19
- fruit fly(34630) Peroxin 19
- dog(478972) peroxisomal biogenesis factor 19
- Zebrafish(324778) peroxisomal biogenesis factor 19
- domestic cat(101094898) peroxisomal biogenesis factor 19
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-PEX19 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
western blot
western blot
Anti-PEX19 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
western blot
Anti-PEX19 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
western blot
Anti-PEX19 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human
Aplicación
ELISA
western blot
western blot
Monoclonal Anti-PEX19 antibody produced in mouse, clone 2E4, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
western blot
western blot