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Merck

PARN

poly(A)-specific ribonuclease

Sinónimos:
DAN
Especie:
ID UniProtKB:
ID del gen:
  • Human(5073) Summary: The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
  • Mouse(74108) poly(A)-specific ribonuclease (deadenylation nuclease)
  • Rat(360464) poly(A)-specific ribonuclease
  • sheep(101112185) poly(A)-specific ribonuclease
  • naked mole-rat(101715275) poly(A)-specific ribonuclease
  • Domestic Rabbit(100351489) poly(A)-specific ribonuclease
  • domestic guinea pig(100732149) poly(A)-specific ribonuclease
  • Zebrafish(791461) poly(A)-specific ribonuclease (deadenylation nuclease)
  • cow(524155) poly(A)-specific ribonuclease
  • chicken(416423) poly(A)-specific ribonuclease
  • domestic cat(101100021) poly(A)-specific ribonuclease
  • dog(479839) poly(A)-specific ribonuclease

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ELISA

Referencia del producto
Descripción
Especie
Mouse Parn / Poly(A)-specific Ribonuclease PARN ELISA Kit, for serum, plasma and cell culture supernatants,
Especie
mouse

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-PARN antibody produced in rabbit, Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
Anti-PARN antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
Anti-PARN antibody produced in rabbit, IgG fraction of antiserum,
Reactividad de especies
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Aplicación
western blot
Anti-PARN antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human, mouse, rat
Aplicación
immunofluorescence
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human PARN,
Especie
human
MISSION® esiRNA, targeting mouse Parn,
Especie
mouse