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Merck

NKX2-1

NK2 homeobox 1

Sinónimos:
BCH, BHC, NK-2, NKX2.1, NKX2A, TEBP, TITF1, TTF-1, TTF1
Especie:
ID UniProtKB:
ID del gen:
  • Human(7080) Summary: This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TFF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. [provided by RefSeq, Apr 2011]
  • Mouse(21869) NK2 homeobox 1
  • Rat(25628) NK2 homeobox 1
  • chicken(395322) NK2 homeobox 1
  • dog(403940) NK2 homeobox 1
  • domestic cat(101091876) NK2 homeobox 1
  • naked mole-rat(101703474) NK2 homeobox 1

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Nkx2.1 Antibody, clone 8G7-G3-1, ascites fluid, clone 8G7-G3-1, Chemicon®,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-TTF1 (Thyroid transcription factor 1) antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM373, purified immunoglobulin,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-Thyroid Transcription Factor-1 antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP141, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
flow cytometry
immunohistochemistry
Monoclonal Anti-TITF1 antibody produced in mouse, clone 2F6, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
western blot
Monoclonal Anti-Nkx2-1 Antibody Produced In Mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL14531, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot