KLRC1
killer cell lectin-like receptor subfamily C, member 1
Sinónimos:
CD159A, NKG2, NKG2A
Especie:
Human KLRC1 (3821), Mouse Klrc1 (16641), Rat Klrc1 (29683), naked mole-rat Klrc1 (101713681), cow KLRC1 (783419), cow KLRC1 (514897)
ID UniProtKB:
ID del gen:
- Human(3821) Summary: Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
- Mouse(16641) killer cell lectin-like receptor subfamily C, member 1
- Rat(29683) killer cell lectin-like receptor subfamily C, member 1
- naked mole-rat(101713681) killer cell lectin-like receptor subfamily C, member 1
- cow(783419) NKG2A-like
- cow(514897) killer cell lectin-like receptor subfamily C, member 1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-NKG2A/C/E Antibody, ,
Reactividad de especies
mouse
Aplicación
flow cytometry
inhibition assay
inhibition assay
Anti-KLRC1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
western blot
Anti-KLRC1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human, mouse
Aplicación
western blot
esiRNA
Referencia del producto
Descripción
Especie