IPO5
importin 5
Sinónimos:
IMB3, KPNB3, Pse1, RANBP5, imp5
Especie:
Human IPO5 (3843), Mouse Ipo5 (70572), Rat Ipo5 (306182), chicken IPO5 (418783), dog IPO5 (485528), cow IPO5 (508273), Horse IPO5 (100060424), domestic cat IPO5 (101097780), sheep IPO5 (101109716), domestic guinea pig Ipo5 (100714433)
ID UniProtKB:
ID del gen:
- Human(3843) Summary: Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family. [provided by RefSeq, Jul 2008]
- Mouse(70572) importin 5
- Rat(306182) importin 5
- chicken(418783) importin 5
- dog(485528) importin 5
- cow(508273) importin 5
- Horse(100060424) importin 5
- domestic cat(101097780) importin 5
- sheep(101109716) importin 5
- domestic guinea pig(100714433) importin 5
- naked mole-rat(101718849) importin 5
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-IPO5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-Importin 5 (N-terminal) antibody produced in rabbit, ~1.0 mg/mL, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-IPO5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-Importin 5 (C-terminal) antibody produced in rabbit, ~1.0 mg/mL, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot