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Merck

IMPDH1

IMP (inosine 5'-monophosphate) dehydrogenase 1

Sinónimos:
IMPD, IMPD1, LCA11, RP10, sWSS2608
Especie:
ID UniProtKB:
ID del gen:
  • Human(3614) Summary: The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
  • Mouse(23917) inosine 5'-phosphate dehydrogenase 1
  • Rat(362329) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • sheep(101104144) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • Domestic Rabbit(100357217) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • domestic guinea pig(100717020) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • naked mole-rat(101720344) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • cow(504305) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • domestic cat(101084274) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • Horse(100071737) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • dog(608783) IMP (inosine 5'-monophosphate) dehydrogenase 1

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Monoclonal Anti-IMPDH1 antibody produced in mouse, clone 3G6, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
western blot
Anti-IMPDH1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
western blot
Anti-IMPDH1 Antibody, clone 4F9.1, clone 4F9.1, from mouse,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
Anti-IMPDH1 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Aplicación
immunohistochemistry
western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
Ribavirin, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human
Ribavirin, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Ribavirin impurity standard, British Pharmacopoeia (BP) Reference Standard,
Especie
human
Ribavirin, European Pharmacopoeia (EP) Reference Standard,
Especie
human
Ribavirin, British Pharmacopoeia (BP) Reference Standard,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human IMPDH1,
Especie
human
MISSION® esiRNA, targeting mouse Impdh1,
Especie
mouse