HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
Sinónimos:
DFNB39, F-TCF, HGFB, HPTA, SF
Especie:
Human HGF (3082), Mouse Hgf (15234), Rat Hgf (24446), domestic guinea pig Hgf (100730730), naked mole-rat Hgf (101707056), sheep HGF (443075), Domestic Rabbit HGF (100316908), chicken HGF (395941), cow HGF (282879), domestic cat HGF (493705)
ID UniProtKB:
ID del gen:
- Human(3082) Summary: Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
- Mouse(15234) hepatocyte growth factor
- Rat(24446) hepatocyte growth factor
- domestic guinea pig(100730730) hepatocyte growth factor (hepapoietin A; scatter factor)
- naked mole-rat(101707056) hepatocyte growth factor (hepapoietin A; scatter factor)
- sheep(443075) hepatocyte growth factor (hepapoietin A; scatter factor)
- Domestic Rabbit(100316908) hepatocyte growth factor (hepapoietin A; scatter factor)
- chicken(395941) hepatocyte growth factor (hepapoietin A; scatter factor)
- cow(282879) hepatocyte growth factor (hepapoietin A; scatter factor)
- domestic cat(493705) hepatocyte growth factor (hepapoietin A; scatter factor)
- dog(403441) hepatocyte growth factor (hepapoietin A; scatter factor)
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ELISA
Referencia del producto
Descripción
Especie
Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-HGF antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, dog, horse, human, mouse, pig, rabbit, rat
Aplicación
western blot
Anti-HGF (ab2) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, dog, horse, human, mouse, pig, rabbit, rat, sheep
Aplicación
immunohistochemistry
western blot
western blot
Anti-HGF antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-HGF antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human, mouse
Aplicación
proximity ligation assay
western blot
western blot
Anti-HGF (ab1) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Aplicación
immunohistochemistry
western blot
western blot
Proteins
Referencia del producto
Descripción
Especie
Hepatocyte Growth Factor human, HGF, recombinant, expressed in HEK 293 cells, HumanKine®, suitable for cell culture,
Especie
human
Hepatocyte Growth Factor human, HGF, recombinant, expressed in NSO cells, suitable for cell culture,
Especie
human
Hepatocyte Growth Factor human, HGF, recombinant, expressed in Baculovirus infected High-5 cells, suitable for cell culture,
Especie
human
HGF mouse, recombinant, expressed in Hi-5 Insect cells, ≥95% (SDS-PAGE), ≥95% (HPLC),
Especie
mouse