FPGT
fucose-1-phosphate guanylyltransferase
Sinónimos:
GFPP
Especie:
Human FPGT (8790), Mouse Fpgt (75540), Rat Fpgt (310935), domestic guinea pig Fpgt (100718633), Domestic Rabbit FPGT (100533991), Zebrafish fpgt (553792), dog FPGT (100533995), cow FPGT (100138313), Horse FPGT (100533993), domestic cat FPGT (101085816)
ID UniProtKB:
ID del gen:
- Human(8790) Summary: L-fucose is a key sugar in glycoproteins and other complex carbohydrates since it may be involved in many of the functional roles of these macromolecules, such as in cell-cell recognition. The fucosyl donor for these fucosylated oligosaccharides is GDP-beta-L-fucose. There are two alternate pathways for the biosynthesis of GDP-fucose; the major pathway converts GDP-alpha-D-mannose to GDP-beta-L-fucose. The protein encoded by this gene participates in an alternate pathway that is present in certain mammalian tissues, such as liver and kidney, and appears to function as a salvage pathway to reutilize L-fucose arising from the turnover of glycoproteins and glycolipids. This pathway involves the phosphorylation of L-fucose to form beta-L-fucose-1-phosphate, and then condensation of the beta-L-fucose-1-phosphate with GTP by fucose-1-phosphate guanylyltransferase to form GDP-beta-L-fucose. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream TNNI3 interacting kinase (TNNI3K) gene. [provided by RefSeq, Dec 2010]
- Mouse(75540) fucose-1-phosphate guanylyltransferase
- Rat(310935) fucose-1-phosphate guanylyltransferase
- domestic guinea pig(100718633) fucose-1-phosphate guanylyltransferase
- Domestic Rabbit(100533991) fucose-1-phosphate guanylyltransferase
- Zebrafish(553792) fucose-1-phosphate guanylyltransferase
- dog(100533995) fucose-1-phosphate guanylyltransferase
- cow(100138313) fucose-1-phosphate guanylyltransferase
- Horse(100533993) fucose-1-phosphate guanylyltransferase
- domestic cat(101085816) fucose-1-phosphate guanylyltransferase
- chicken(100533998) fucose-1-phosphate guanylyltransferase
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-FPGT antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
western blot
Anti-FPGT antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
western blot