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Merck

FMR1

fragile X mental retardation 1

Sinónimos:
FMRP, FRAXA, POF, POF1
Especie:
Human FMR1 (2332), Mouse Fmr1 (14265), Rat Fmr1 (24948), Zebrafish fmr1 (259191), cow FMR1 (507482), domestic cat FMR1 (101080266), dog FMR1 (481070), chicken FMR1 (422395), fruit fly Fmr1 (37528), sheep FMR1 (101117478) ...Más
ID UniProtKB:
Q06787, A6NNH4, D3DWT0, D3DWT1, D3DWT2, Q16578, Q5PQZ6, Q99054
ID del gen:
  • Human(2332) Summary: The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. [provided by RefSeq, May 2010]
  • Mouse(14265) fragile X mental retardation syndrome 1
  • Rat(24948) fragile X mental retardation 1
  • Zebrafish(259191) fragile X mental retardation 1
  • cow(507482) fragile X mental retardation 1
  • domestic cat(101080266) fragile X mental retardation 1
  • dog(481070) fragile X mental retardation 1
  • chicken(422395) fragile X mental retardation 1
  • fruit fly(37528) CG6203 gene product from transcript CG6203-RC
  • sheep(101117478) fragile X mental retardation 1
  • naked mole-rat(101707722) fragile X mental retardation 1
  • domestic guinea pig(100734782) fragile X mental retardation 1

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
MABN2280
Anti-FMR1polyG Antibody, clone 8FM-2F7, ascites fluid, clone 8FM-2F7, from mouse,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
western blot
SAB1403834
Monoclonal Anti-FMR1 antibody produced in mouse, clone 3E11, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
western blot
HPA050118
Anti-FMR1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
HPA056084
Anti-FMR1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
SAB1105888
Anti-FMR1 (36-49) antibody produced in rabbit, IgG fraction of antiserum,
Reactividad de especies
human
Aplicación
western blot

esiRNA

Referencia del producto
Descripción
Especie
EMU039161
MISSION® esiRNA, targeting mouse Fmr1,
Especie
mouse
EHU082131
MISSION® esiRNA, targeting human FMR1,
Especie
human
EHU222651
MISSION® esiRNA, targeting human FMR1-AS1,
Especie
human