FGFR2
fibroblast growth factor receptor 2
Sinónimos:
BBDS, BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25
Especie:
Human FGFR2 (2263), Mouse Fgfr2 (14183), Rat Fgfr2 (25022), Zebrafish fgfr2 (352940), Horse FGFR2 (100033956), domestic cat FGFR2 (101095198), cow FGFR2 (404193), chicken FGFR2 (396259), dog FGFR2 (415125), domestic guinea pig Fgfr2 (100379152) ...Más
ID UniProtKB:
ID del gen:
- Human(2263) Summary: The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2009]
- Mouse(14183) fibroblast growth factor receptor 2
- Rat(25022) fibroblast growth factor receptor 2
- Zebrafish(352940) fibroblast growth factor receptor 2
- Horse(100033956) fibroblast growth factor receptor 2
- domestic cat(101095198) fibroblast growth factor receptor 2
- cow(404193) fibroblast growth factor receptor 2
- chicken(396259) fibroblast growth factor receptor 2
- dog(415125) fibroblast growth factor receptor 2
- domestic guinea pig(100379152) fibroblast growth factor receptor 2
- naked mole-rat(101709077) fibroblast growth factor receptor 2
- sheep(443548) fibroblast growth factor receptor 2
- Domestic Rabbit(100009417) fibroblast growth factor receptor 2
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Referencia del producto
Descripción
Especie
Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Fibroblast Growth Factor Receptor-2, Cytoplasmic antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
western blot
Monoclonal Anti-FGFR2 antibody produced in mouse, clone 1G3, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-FGFR2 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse
Aplicación
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-FGFR2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-Fibroblast Growth Factor Receptor-2, Extracellular antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
western blot
Proteins
Referencia del producto
Descripción
Especie
FGFR2 Protein, active, 10 µg, Active, N-terminal, His6-tagged, recombinant, human FGFR2, amino acids 456-770, for use in Kinase Assays.,
Especie
human
FGFR2 (N549H) Protein, active, 10 µg, Active, N-terminal, 6His-tagged, recombinant, human FGFR2 (N549H), amino acids 456-770. For use in Kinase Assays.,
Especie
human
FGFR2 (285-end), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥80% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human
esiRNA
Referencia del producto
Descripción
Especie