CREBBP
CREB binding protein
Sinónimos:
CBP, KAT3A, RSTS
Especie:
Human CREBBP (1387), Mouse Crebbp (12914), Rat Crebbp (54244), Zebrafish crebbp (100535787), dog CREBBP (479866), Horse CREBBP (100069613), domestic cat CREBBP (101094471), chicken CREBBP (416667), cow CREBBP (505453), naked mole-rat Crebbp (101714025) ...Más
ID UniProtKB:
ID del gen:
- Human(1387) Summary: This gene is ubiquitously expressed and is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. The protein encoded by this gene has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. This protein acetylates both histone and non-histone proteins. This protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain. Mutations in this gene cause Rubinstein-Taybi syndrome (RTS). Chromosomal translocations involving this gene have been associated with acute myeloid leukemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2009]
- Mouse(12914) CREB binding protein
- Rat(54244) CREB binding protein
- Zebrafish(100535787) CREB binding protein
- dog(479866) CREB binding protein
- Horse(100069613) CREB binding protein
- domestic cat(101094471) CREB binding protein
- chicken(416667) CREB binding protein
- cow(505453) CREB binding protein
- naked mole-rat(101714025) CREB binding protein
- domestic guinea pig(100716770) CREB binding protein
- sheep(101123600) CREB binding protein
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-CREBBP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-CREB-BP antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse
Aplicación
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-CBP antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Monoclonal Anti-CREBBP antibody produced in mouse, clone 2B6, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
western blot
western blot
Anti-CREBBP antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Aplicación
immunohistochemistry
western blot
western blot
Proteins
Referencia del producto
Descripción
Especie
CBP (1319-1710), GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human
KAT3A (518-1207), GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human