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Merck

CBX1

chromobox homolog 1

Sinónimos:
CBX, HP1-BETA, HP1Hs-beta, HP1Hsbeta, M31, MOD1, p25beta
Especie:
ID UniProtKB:
ID del gen:
  • Human(10951) Summary: This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(12412) chromobox 1
  • Rat(360609) chromobox homolog 1
  • naked mole-rat(101706928) chromobox homolog 1
  • domestic guinea pig(100716439) chromobox homolog 1
  • sheep(101116158) chromobox homolog 1
  • chicken(374237) chromobox homolog 1
  • domestic cat(101084070) chromobox homolog 1
  • cow(616506) chromobox homolog 1
  • dog(491051) chromobox homolog 1

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Heterochromatin Protein-1 β Antibody, clone 1MOD-1A9, ascites fluid, clone 1MOD-1A9, Chemicon®,
Reactividad de especies
human, mouse
Aplicación
ELISA
immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-CBX1 (HP1 beta) Antibody, clone 5E9.1, clone 5E9.1, from mouse,
Reactividad de especies
human
Aplicación
western blot
Anti-CBX1, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, dog, horse, human, mouse, pig, rabbit, rat, yeast
Aplicación
western blot
Anti-CBX1/HP1-β antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
canine, human, mouse, rat
Aplicación
ELISA
immunohistochemistry

western blot
Monoclonal Anti-CBX1 antibody produced in mouse, clone 4E12, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
immunofluorescence

western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human CBX1,
Especie
human