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Merck

CACNA1E

calcium channel, voltage-dependent, R type, alpha 1E subunit

Sinónimos:
BII, CACH6, CACNL1A6, Cav2.3
Especie:
ID UniProtKB:
ID del gen:
  • Human(777) Summary: Voltage-dependent calcium channels are multisubunit complexes consisting of alpha-1, alpha-2, beta, and delta subunits in a 1:1:1:1 ratio. These channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This gene encodes the alpha-1E subunit of the R-type calcium channels, which belong to the 'high-voltage activated' group that maybe involved in the modulation of firing patterns of neurons important for information processing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011]
  • Mouse(12290) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • Rat(54234) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • Zebrafish(567702) voltage-dependent R-type calcium channel subunit alpha-1E
  • cow(353113) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • domestic cat(101093985) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • dog(490305) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • chicken(424412) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • naked mole-rat(101701145) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • domestic guinea pig(100716749) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • sheep(101102503) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • Domestic Rabbit(100009403) calcium channel, voltage-dependent, R type, alpha 1E subunit

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Small Molecule - Allosteric Modulator

Referencia del producto
Descripción
Especie
Gabapentin, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Gabapentin solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Especie
human
Gabapentin solution, 10 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Especie
human
Gabapentin, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human
Pregabalin, European Pharmacopoeia (EP) Reference Standard,
Especie
human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-CACNA1S antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-CACNA1S antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Monoclonal Anti-Dihydropyridine Receptor (α1 Subunit) antibody produced in mouse, clone 1A, buffered aqueous solution,
Reactividad de especies
guinea pig, human, mouse, rabbit, rat
Aplicación
immunohistochemistry
immunoprecipitation (IP)

western blot

Small Molecule - Blocker

Referencia del producto
Descripción
Especie
Verapamil hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Amlodipine besylate, ≥98% (HPLC),
Especie
human
Amlodipine besylate, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Nicardipine hydrochloride, powder, ≥98%,
Especie
human
Verapamil hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Cacna1e,
Especie
mouse
MISSION® esiRNA, targeting human CACNA1E,
Especie
human
MISSION® esiRNA, targeting human CACNA1S,
Especie
human
MISSION® esiRNA, targeting mouse Cacna1s,
Especie
mouse