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Merck

BPGM

2,3-bisphosphoglycerate mutase

Sinónimos:
DPGM
Especie:
ID UniProtKB:
ID del gen:
  • Human(669) Summary: 2,3-diphosphoglycerate (2,3-DPG) is a small molecule found at high concentrations in red blood cells where it binds to and decreases the oxygen affinity of hemoglobin. This gene encodes a multifunctional enzyme that catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. The enzyme also has phosphoglycerate phosphomutase activity. Deficiency of this enzyme increases the affinity of cells for oxygen. Mutations in this gene result in hemolytic anemia. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2009]
  • Mouse(12183) 2,3-bisphosphoglycerate mutase
  • Rat(296973) 2,3-bisphosphoglycerate mutase
  • Zebrafish(436903) 2,3-bisphosphoglycerate mutase
  • dog(482704) 2,3-bisphosphoglycerate mutase
  • domestic cat(101095644) 2,3-bisphosphoglycerate mutase
  • cow(533785) 2,3-bisphosphoglycerate mutase
  • chicken(418172) 2,3-bisphosphoglycerate mutase
  • domestic guinea pig(100722842) 2,3-bisphosphoglycerate mutase
  • naked mole-rat(101706859) 2,3-bisphosphoglycerate mutase
  • sheep(101121089) 2,3-bisphosphoglycerate mutase
  • Domestic Rabbit(100009096) 2,3-bisphosphoglycerate mutase

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-BPGM antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
Anti-BPGM antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry

western blot
Anti-BPGM (ab2) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human
Aplicación
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human BPGM,
Especie
human
MISSION® esiRNA, targeting mouse Bpgm,
Especie
mouse