AXIN1
axin 1
Sinónimos:
AXIN, PPP1R49
Especie:
Human AXIN1 (8312), Mouse Axin1 (12005), Rat Axin1 (79257), Zebrafish axin1 (57931), cow AXIN1 (504357), Horse AXIN1 (100065116), domestic cat AXIN1 (101088804), dog AXIN1 (490099), chicken AXIN1 (395786), sheep AXIN1 (101122656) ...Más
ID UniProtKB:
ID del gen:
- Human(8312) Summary: This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta-1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Dec 2010]
- Mouse(12005) axin 1
- Rat(79257) axin 1
- Zebrafish(57931) axin 1
- cow(504357) axin 1
- Horse(100065116) axin 1
- domestic cat(101088804) axin 1
- dog(490099) axin 1
- chicken(395786) axin 1
- sheep(101122656) axin 1
- domestic guinea pig(100718536) axin 1
- naked mole-rat(101700795) axin 1
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Axin-1 Antibody, from rabbit, purified by affinity chromatography,
Reactividad de especies
human, mouse
Aplicación
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-AXIN1 antibody produced in mouse, clone 2B11, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
immunofluorescence
proximity ligation assay
western blot
immunofluorescence
proximity ligation assay
western blot
Anti-Axin1 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
western blot
western blot
Anti-Axin-1 Antibody, clone A5, clone A5, from mouse,
Reactividad de especies
human, mouse
Aplicación
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-Axin1 (C-terminal region) antibody produced in rabbit, ~2.5 mg/mL, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
western blot