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Merck

ALDOB

aldolase B, fructose-bisphosphate

Sinónimos:
ALDB, ALDO2
Especie:
ID UniProtKB:
ID del gen:
  • Human(229) Summary: Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance. [provided by RefSeq, Dec 2008]
  • Mouse(230163) aldolase B, fructose-bisphosphate
  • Rat(24190) aldolase B, fructose-bisphosphate
  • domestic guinea pig(100720708) aldolase B, fructose-bisphosphate
  • naked mole-rat(101713582) aldolase B, fructose-bisphosphate
  • sheep(443440) aldolase B, fructose-bisphosphate
  • Domestic Rabbit(100328925) aldolase B, fructose-bisphosphate
  • Zebrafish(321664) aldolase b, fructose-bisphosphate
  • cow(515263) aldolase B, fructose-bisphosphate
  • Horse(100054480) aldolase B, fructose-bisphosphate
  • domestic cat(101097025) aldolase B, fructose-bisphosphate
  • dog(474787) aldolase B, fructose-bisphosphate
  • chicken(427308) aldolase B, fructose-bisphosphate

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-ALDOB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-ALDOB antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
western blot
Anti-Aldob Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
Anti-ALDOB antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
dog, guinea pig, horse, human, mouse, rabbit, rat
Aplicación
western blot
Anti-ALDOB antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
western blot

Kits

Referencia del producto
Descripción
Especie
Aldolase Activity Colorimetric Assay Kit, Sufficient for 100 Colorimetric tests,
Especie
mouse, human, rat

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human ALDOB,
Especie
human