07964
Methoxypolyethylene glycol amine
750
Synonym(s):
mPEG-NH2, O-(2-Aminoethyl)-O′-methylpolyethylene glycol, Aminopolyethylene glycol monomethyl ether, Methoxypolyoxyethylene amine
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About This Item
Linear Formula:
H2NCH2CH2(OCH2CH2)nOCH3
CAS Number:
MDL number:
UNSPSC Code:
12162002
NACRES:
NA.22
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Quality Level
form
solid
color
white to yellow
InChI
1S/C3H9NO/c1-5-3-2-4/h2-4H2,1H3
InChI key
ASUDFOJKTJLAIK-UHFFFAOYSA-N
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Application
Methoxypolyethylene glycol amine can:
- Form dendritic micelles to enhance the solubility of hydrophobic compounds.
- Conjugate with an anticancer drug methotrexate (MTX) to form MTX-PEG with potential application as drug carriers.
- Couple with polyethylenimine (PEI) to form graft copolymers which can be used as nonviral gene vectors.
Other Notes
Oligomer used to prepare PEG-ylated conjugates having the advantage of reduced immunogenicity and increased serum half life
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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