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16905

Sigma-Aldrich

Fmoc-D-Ile-OH

≥96.0% (HPLC), for peptide synthesis

Synonym(s):

Fmoc-D-isoleucine

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About This Item

Empirical Formula (Hill Notation):
C21H23NO4
CAS Number:
143688-83-9
Molecular Weight:
353.41
MDL number:
MFCD00080291
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
57647593
NACRES:
NA.26

product name

Fmoc-D-Ile-OH, ≥96.0% (HPLC)

Assay

≥96.0% (HPLC)

form

solid

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

application(s)

peptide synthesis

functional group

Fmoc

SMILES string

CC[C@@H](C)[C@@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O

InChI

1S/C21H23NO4/c1-3-13(2)19(20(23)24)22-21(25)26-12-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,13,18-19H,3,12H2,1-2H3,(H,22,25)(H,23,24)/t13-,19-/m1/s1

InChI key

QXVFEIPAZSXRGM-BFUOFWGJSA-N

General description

Fmoc-D-Ile-OH is an amino acid in which Fmoc is a protected form of D-Isoleucine.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Binu Jacob et al.
Amino acids, 48(5), 1241-1251 (2016-01-23)
Sheep myeloid antimicrobial peptide-29 (SMAP-29) is a cathelicidin-related antimicrobial peptide derived from sheep myeloid cells. In order to investigate the effects of L-to-D-amino acid substitution in SMAP-29 on bacterial selectivity, membrane interaction and anti-inflammatory activity, we synthesized its two D-enantiomeric
Andreas Pech et al.
Nucleic acids research, 45(7), 3997-4005 (2017-02-06)
Biological evolution resulted in a homochiral world in which nucleic acids consist exclusively of d-nucleotides and proteins made by ribosomal translation of l-amino acids. From the perspective of synthetic biology, however, particularly anabolic enzymes that could build the mirror-image counterparts

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