TK2
thymidine kinase 2, mitochondrial
Synonyms:
MTDPS2, MTTK
Species:
Human TK2 (7084), Mouse Tk2 (57813), Rat Tk2 (291824), Zebrafish tk2 (437016), domestic cat TK2 (101085008), Horse TK2 (100065312), dog TK2 (611387), chicken TK2 (427551), naked mole-rat Tk2 (101704299), domestic guinea pig Tk2 (100727406) ...More
UniProtKB ID:
Gene ID:
- Human(7084) Summary: This gene encodes a deoxyribonucleoside kinase that specifically phosphorylates thymidine, deoxycytidine, and deoxyuridine. The encoded enzyme localizes to the mitochondria and is required for mitochondrial DNA synthesis. Mutations in this gene are associated with a myopathic form of mitochondrial DNA depletion syndrome. Alternate splicing results in multiple transcript variants encoding distinct isoforms, some of which lack transit peptide, so are not localized to mitochondria. [provided by RefSeq, Dec 2012]
- Mouse(57813) thymidine kinase 2, mitochondrial
- Rat(291824) thymidine kinase 2, mitochondrial
- Zebrafish(437016) thymidine kinase 2, mitochondrial
- domestic cat(101085008) thymidine kinase 2, mitochondrial
- Horse(100065312) thymidine kinase 2, mitochondrial
- dog(611387) thymidine kinase 2, mitochondrial
- chicken(427551) thymidine kinase 2, mitochondrial
- naked mole-rat(101704299) thymidine kinase 2, mitochondrial
- domestic guinea pig(100727406) thymidine kinase 2, mitochondrial
- cow(615457) thymidine kinase 2, mitochondrial
- sheep(101103665) thymidine kinase 2, mitochondrial
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-TK2 (N-term) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ELISA
western blot
western blot
Anti-TK2 (C-term) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-TK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse
Application
immunohistochemistry
Small Molecule - Inhibitor
Product Number
Description
Species