LPIN1
lipin 1
Synonyms:
PAP1
Species:
Human LPIN1 (23175), Mouse Lpin1 (14245), Rat Lpin1 (313977), Zebrafish lpin1 (799099), dog LPIN1 (475670), Horse LPIN1 (100072273), cow LPIN1 (537224), domestic cat LPIN1 (101085623), chicken LPIN1 (421945), sheep LPIN1 (101120647) ...More
UniProtKB ID:
Gene ID:
- Human(23175) Summary: This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their full-length structures have not been determined. [provided by RefSeq, May 2012]
- Mouse(14245) lipin 1
- Rat(313977) lipin 1
- Zebrafish(799099) lipin 1
- dog(475670) lipin 1
- Horse(100072273) lipin 1
- cow(537224) lipin 1
- domestic cat(101085623) lipin 1
- chicken(421945) lipin 1
- sheep(101120647) lipin 1
- domestic guinea pig(100718634) lipin 1
- Domestic Rabbit(100346262) lipin 1
- naked mole-rat(101721483) lipin 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-LPIN1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
dog, horse, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot
western blot
Monoclonal Anti-LPIN1, (C-terminal) antibody produced in mouse, clone 3D9, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-LPIN1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Lipin-1 Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human, mouse
Application
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-LPIN1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence