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ALDH5A1

aldehyde dehydrogenase 5 family, member A1

Synonyms:
SSADH, SSDH
Species:
UniProtKB ID:
Gene ID:
  • Human(7915) Summary: This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(214579) aldhehyde dehydrogenase family 5, subfamily A1
  • Rat(291133) aldehyde dehydrogenase 5 family, member A1
  • naked mole-rat(101723101) aldehyde dehydrogenase 5 family, member A1
  • domestic guinea pig(100735182) aldehyde dehydrogenase 5 family, member A1
  • sheep(101107828) aldehyde dehydrogenase 5 family, member A1
  • Domestic Rabbit(100351836) aldehyde dehydrogenase 5 family, member A1
  • Zebrafish(565235) aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase)
  • cow(532724) aldehyde dehydrogenase 5 family, member A1
  • domestic cat(101088238) aldehyde dehydrogenase 5 family, member A1
  • dog(488246) aldehyde dehydrogenase 5 family, member A1
  • chicken(420818) aldehyde dehydrogenase 5 family, member A1

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ALDH5A1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
Anti-ALDH5A1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
canine, human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-ALDH5A1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
bovine, canine, human, mouse, rat
Application
ELISA
western blot
Anti-ALDH5A1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, ab2,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-ALDH5A1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, ab1,
Species Reactivity
human
Application
immunohistochemistry
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Sodium valproate, British Pharmacopoeia (BP) Reference Standard,
Species
human
Valproic acid, European Pharmacopoeia (EP) Reference Standard,
Species
human
Valproic acid, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Valproic acid, United States Pharmacopeia (USP) Reference Standard,
Species
human
Sodium valproate, European Pharmacopoeia (EP) Reference Standard,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Aldh5a1,
Species
mouse
MISSION® esiRNA, targeting human ALDH5A1,
Species
human