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Merck

ACACB

acetyl-CoA carboxylase beta

Synonyms:
ACC2, ACCB, HACC275
Species:
UniProtKB ID:
Gene ID:
  • Human(32) Summary: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. ACC-beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. ACC-beta may be involved in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. There is evidence for the presence of two ACC-beta isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(100705) acetyl-Coenzyme A carboxylase beta
  • Rat(116719) acetyl-CoA carboxylase beta
  • naked mole-rat(101717399) acetyl-CoA carboxylase beta
  • domestic guinea pig(100728089) acetyl-CoA carboxylase beta
  • sheep(101114816) acetyl-CoA carboxylase beta
  • Zebrafish(556236) acetyl-CoA carboxylase beta
  • domestic cat(101086680) acetyl-CoA carboxylase beta
  • Horse(100066740) acetyl-CoA carboxylase beta
  • cow(515338) acetyl-CoA carboxylase beta
  • dog(100685468) acetyl-CoA carboxylase beta
  • chicken(430557) acetyl-CoA carboxylase beta

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-ACACB antibody produced in mouse, clone 1C11, ascites fluid,
Species Reactivity
human
Application
ELISA
western blot
Anti-ACACB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot

Proteins

Product Number
Description
Species
Acetyl-CoA carboxylase 2 human, recombinant, expressed in Sf9 cells,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human ACACB,
Species
human
MISSION® esiRNA, targeting mouse Acacb,
Species
mouse