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34130

Supelco

Fusarenon X solution

100 μg/mL in acetonitrile, analytical standard

Synonym(s):

3α,7α,15-Trihydroxy-4β-acetoxy-12,13-epoxytrichothec-9-en-8-one, FusX

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About This Item

Empirical Formula (Hill Notation):
C17H22O8
CAS Number:
23255-69-8
Molecular Weight:
354.35
EC Number:
200-835-2
MDL number:
MFCD00078778
UNSPSC Code:
41116107
PubChem Substance ID:
329754836
NACRES:
NA.24

grade

analytical standard

shelf life

limited shelf life, expiry date on the label

concentration

100 μg/mL in acetonitrile

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

single component solution

storage temp.

−20°C

SMILES string

CC(=O)O[C@@H]1[C@@H](O)[C@H]2O[C@@H]3C=C(C)C(=O)[C@@H](O)[C@]3(CO)[C@]1(C)[C@]24CO4

InChI

1S/C17H22O8/c1-7-4-9-16(5-18,12(22)10(7)20)15(3)13(24-8(2)19)11(21)14(25-9)17(15)6-23-17/h4,9,11-14,18,21-22H,5-6H2,1-3H3/t9-,11-,12-,13-,14-,15-,16-,17+/m1/s1

InChI key

XGCUCFKWVIWWNW-CAYGJDLQSA-N

General description

Certan Vial
Fusarenon X, is a trichothecene mycotoxin, which is produced by Fusarium nivale fungi, naturally occurring in crops such as wheat and barley.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

35.6 °F - closed cup

Flash Point(C)

2 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCK3026
BCCG5947
BCCF6544
BCCC8509
BCCB3655

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Low tumor incidence in rats with long-term feeding of fusarenon-X, a cytotoxic trichothecene produced by Fusarium nivale
Saito M, et al.
The Japanese Journal of Experimental Medicine, 50, 293-302 (1980)
Fusarenon-X induced apoptosis in HL-60 cells depends on caspase activation and cytochrome c release
Miura K, et al.
Toxicology, 172, 103-112 (2002)
The fates of trichothecene mycotoxins, nivalenol and fusarenon-X, in mice
Poapolathep A, et al.
Toxicon, 41, 1047-1054 (2003)
J Li et al.
The Journal of veterinary medical science, 59(3), 191-199 (1997-03-01)
Male 5-week-old Wistar rats orally (po) administered with fusarenon-X (FX) 1.5 mg/kg and control rats po-treated with distilled water were sacrificed at 0-48 hr after gavage. FX-administered rats showed significant dilatation of the stomach with increased fluid contents at 1-24
S Bony et al.
Toxicology in vitro : an international journal published in association with BIBRA, 21(3), 457-465 (2006-12-13)
This study aims to assess the genotoxic potential of nivalenol (NIV) and fusarenon X (FusX), produced by various Fusarium on cereals. Toxins were applied in time and dose-dependent experiments to the human enterocyte-like Caco-2 cell-line, both in dividing (undifferentiated) and
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