14-909-M
MELK Protein, active, 0 0
Active, recombinant human MELK (amino acids 1 -340), containing an N-terminal GST tag, for use in Kinase Assays.
Synonym(s):
HPK38, PK38, pEg3 kinase
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About This Item
UNSPSC Code:
12352200
eCl@ss:
32160405
NACRES:
NA.32
biological source
human
Quality Level
100
300
recombinant
expressed in baculovirus infected insect cells
mol wt
Mw 66 kDa
manufacturer/tradename
Upstate®
technique(s)
activity assay: suitable (kinase)
UniProt accession no.
Gene Information
human ... MELK(9833)
General description
Maternal embryonic leucine zipper kinase (MELK) is a conserved serine/threonine kinase involved in a variety of cellular functions, including proliferation, differentiation and apoptosis. Its levels are elevated in a number of tumour types and it may be a prognosis marker for some cancers.
Product Source: Recombinant protein of the human MELK gene expressed by baculovirus in insect cells
Recombinant human MELK (amino acids 1 - 340), containing an N-terminal GST tag
Application
Research Category
Signaling
Signaling
Biochem/physiol Actions
Target Sub-Family: CAMK
Packaging
Also available in 250μg size - call for pricing and availability and reference catalog number 14-909M when ordering the 250μg size
Quality
Routinely evaluated by phosphorylation of KKLNRTLSFAEPG
Physical form
Purified using glutathione-agarose
Storage and Stability
6 months at -70°C
Other Notes
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Skin Sens. 1
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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