SOCS1
suppressor of cytokine signaling 1
Synonyms:
CIS1, CISH1, JAB, SOCS-1, SSI-1, SSI1, TIP3
Species:
Human SOCS1 (8651), Mouse Socs1 (12703), Rat Socs1 (252971), chicken SOCS1 (416630), dog SOCS1 (490006), cow SOCS1 (518795), sheep SOCS1 (101107324), domestic guinea pig Socs1 (100728652), naked mole-rat Socs1 (101729320)
UniProtKB ID:
Gene ID:
- Human(8651) Summary: This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. [provided by RefSeq, Jul 2008]
- Mouse(12703) suppressor of cytokine signaling 1
- Rat(252971) suppressor of cytokine signaling 1
- chicken(416630) suppressor of cytokine signaling 1
- dog(490006) suppressor of cytokine signaling 1
- cow(518795) suppressor of cytokine signaling 1
- sheep(101107324) suppressor of cytokine signaling 1
- domestic guinea pig(100728652) suppressor of cytokine signaling 1
- naked mole-rat(101729320) suppressor of cytokine signaling 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-SOCS1 (ab2) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-SOCS1 Antibody, clone 5T6Z10, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-SOCS1 (ab1) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
western blot
Anti-SOCS1 Antibody, clone 4H1, clone 4H1, Upstate®, from mouse,
Species Reactivity
human, mouse
Application
immunoprecipitation (IP)
western blot
western blot
Anti-SOCS1 antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
bovine, human, mouse, pig, rabbit, rat
Application
immunohistochemistry
western blot
western blot