SMAD7
SMAD family member 7
Synonyms:
CRCS3, MADH7, MADH8
Species:
Human SMAD7 (4092), Mouse Smad7 (17131), Rat Smad7 (81516), Zebrafish smad7 (326282), chicken SMAD7 (429683), dog SMAD7 (490570), Horse SMAD7 (100033853), domestic cat SMAD7 (101088277), cow SMAD7 (535916), sheep SMAD7 (443160) ...More
UniProtKB ID:
Gene ID:
- Human(4092) Summary: The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
- Mouse(17131) SMAD family member 7
- Rat(81516) SMAD family member 7
- Zebrafish(326282) MAD, mothers against decapentaplegic homolog 7 (Drosophila)
- chicken(429683) SMAD family member 7
- dog(490570) SMAD family member 7
- Horse(100033853) SMAD family member 7
- domestic cat(101088277) SMAD family member 7
- cow(535916) SMAD family member 7
- sheep(443160) SMAD family member 7
- domestic guinea pig(100717293) SMAD family member 7
- naked mole-rat(101718588) SMAD family member 7
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-SMAD7 (N-terminal) antibody produced in rabbit, ~1.0 mg/mL, affinity isolated antibody, suitable for western blot: 2 μg/mL,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot
Monoclonal Anti-SMAD7 antibody produced in mouse, clone 4E1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Monoclonal Anti-SMAD7 antibody produced in mouse, clone 3G8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-SMAD7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-SMAD7 Antibody, clone 2D15 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse, rat
Application
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
esiRNA
Product Number
Description
Species