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Merck

SCN4A

sodium channel, voltage-gated, type IV, alpha subunit

Synonyms:
HOKPP2, HYKPP, HYPP, NAC1A, Na(V)1.4, Nav1.4, SkM1
Species:
UniProtKB ID:
Gene ID:
  • Human(6329) Summary: Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family. It is expressed in skeletal muscle, and mutations in this gene have been linked to several myotonia and periodic paralysis disorders. [provided by RefSeq, Jul 2008]
  • Mouse(110880) sodium channel, voltage-gated, type IV, alpha
  • Rat(25722) sodium channel, voltage-gated, type IV, alpha subunit
  • domestic guinea pig(100717730) sodium channel, voltage-gated, type IV, alpha subunit
  • naked mole-rat(101713228) sodium channel, voltage-gated, type IV, alpha subunit
  • cow(517426) sodium channel, voltage-gated, type IV, alpha subunit
  • sheep(101123056) sodium channel, voltage-gated, type IV, alpha subunit
  • chicken(771297) sodium channel, voltage-gated, type IV, alpha subunit
  • Horse(100049793) sodium channel, voltage-gated, type IV, alpha subunit
  • domestic cat(101098669) sodium channel, voltage-gated, type IV, alpha subunit
  • dog(610754) sodium channel, voltage-gated, type IV, alpha subunit

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-SCN4A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Monoclonal Anti-Sodium Channel, Pan antibody produced in mouse, ~1 mg/mL, clone K58/35, purified immunoglobulin,
Species Reactivity
mammals
Application
immunofluorescence
immunohistochemistry

western blot

Small Molecule - Blocker

Product Number
Description
Species
Levobupivacaine hydrochloride, ≥98% (HPLC),
Species
human
Ranolazine dihydrochloride, ≥98% (HPLC), powder,
Species
human
Lidocaine hydrochloride monohydrate, solid,
Species
human
Tetracaine, ≥98% (TLC),
Species
human
Mexiletine hydrochloride, powder,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human SCN4A,
Species
human
MISSION® esiRNA, targeting mouse Scn4a,
Species
mouse