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Merck

RPL10

ribosomal protein L10

Synonyms:
AUTSX5, DXS648, DXS648E, L10, NOV, QM
Species:
UniProtKB ID:
Gene ID:
  • Human(6134) Summary: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of four RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L10E family of ribosomal proteins. It is located in the cytoplasm. In vitro studies have shown that the chicken protein can bind to c-Jun and can repress c-Jun-mediated transcriptional activation, but these activities have not been demonstrated in vivo. This gene was initially identified as a candidate for a Wilms tumor suppressor gene, but later studies determined that this gene is not involved in the suppression of Wilms tumor. This gene has been referred to as 'laminin receptor homolog' because a chimeric transcript consisting of sequence from this gene and sequence from the laminin receptor gene was isolated; however, it is not believed that this gene encodes a laminin receptor. Alternative splicing results in multiple transcript variants. This gene also uses multiple polyA signals, with the 3'-most polyA signal overlapping the deoxyribonuclease I-like 1 gene on the opposite strand. This gene is co-transcribed with the small nucleolar RNA gene U70, which is located in its fifth intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Feb 2012]
  • Mouse(110954) ribosomal protein L10
  • Rat(81764) ribosomal protein L10
  • fruit fly(43864) Ribosomal protein L10
  • Zebrafish(336712) ribosomal protein L10
  • dog(481085) ribosomal protein L10
  • domestic cat(101083663) ribosomal protein L10
  • naked mole-rat(101702793) ribosomal protein L10
  • Domestic Rabbit(100328757) ribosomal protein L10
  • domestic guinea pig(100724614) ribosomal protein L10
  • cow(286790) ribosomal protein L10
  • sheep(100127215) ribosomal protein L10

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-60S Ribosomal Protein L10, N-Terminal antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
Monoclonal Anti-RPL10, (N-terminal) antibody produced in mouse, clone 2C4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Anti-RPL10 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human RPL10,
Species
human