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Merck

HLA-E

major histocompatibility complex, class I, E

Synonyms:
EA1.2, EA2.1, HLA-6.2, MHC, QA1
Species:
Human HLA-E (3133)
UniProtKB ID:
P13747, Q30169, Q9BT83, Q9GIY7, Q9GIY8
Gene ID:
  • Human(3133) Summary: HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. [provided by RefSeq, Jul 2008]

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB4702062
Monoclonal Anti-HLA-E purified produced in mouse, ,
Species Reactivity
human
Application
immunohistochemistry
western blot
SAB1400126
Anti-HLA-E antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
western blot
SAB4700303
Monoclonal Anti-HLA-E-Biotin antibody produced in mouse, clone MEM-E/07, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
SAB4700300
Monoclonal Anti-HLA-E antibody produced in mouse, clone MEM-E/08, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
SAB1401182
Anti-HLA-E antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunoprecipitation (IP)
western blot

esiRNA

Product Number
Description
Species
EHU220931
MISSION® esiRNA, targeting human HLA-E,
Species
human