Synthesis of Heterotelechelic Polymers for Conjugation of Two Different Proteins.

Synthesis of Heterotelechelic Polymers for Conjugation of Two Different Proteins.

Macromolecules (2009-01-01)

Karina L Heredia, Gregory N Grover, Lei Tao, Heather D Maynard

ABSTRACT

In this report we describe a straightforward approach to synthesize polymers with end-groups that bind site-specifically to two different proteins. Telechelic biotin, maleimide poly(

MATERIALS

Product Number

Brand

Product Description

755850

Sigma-Aldrich

11-Maleimidoundecanoic acid, 95% (GC)

731765

Sigma-Aldrich

Poly(ethylene glycol) methyl ether maleimide, average M_n 2,000