- Synthesis, characterisation and cytotoxicity of chloro derivatives of prenylnaphthohydroquinone.
Synthesis, characterisation and cytotoxicity of chloro derivatives of prenylnaphthohydroquinone.
Bioorganic & medicinal chemistry (2005-06-21)
Aurora Molinari, Alfonso Oliva, Claudia Ojeda, Jorge Escobar, Carolina Gallardo, José Ma Miguel del Corral, Ma Angeles Castro, Carmen Cuevas, Arturo San Feliciano
PMID15966071
ABSTRACT
From the Diels-Alder adduct between alpha-myrcene and 2-chloro-1,4-benzoquinone, a family of chloro derivatives of prenylnaphthohydroquinone have been synthesised and evaluated for their cytotoxicity against 14 neoplastic cell lines.
MATERIALS