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  • [Research progress on the efficacy, metabolism and bioavailability of mebendazole in hydatid disease].

[Research progress on the efficacy, metabolism and bioavailability of mebendazole in hydatid disease].

Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases (2010-03-18)
Cong-Shan Liu, Hao-Bing Zhang
ABSTRACT

Mebendazole is currently used in the treatment of hydatid disease. Its poor absorption from the gastrointestinal tract and low bioavailability aroused further research on new formulations of mebendazole to increase the bioavailability and improve the therapeutic efficacy. This review summarizes the recent research progress.

MATERIALS
Product Number
Brand
Product Description

Mebendazole for system suitability, European Pharmacopoeia (EP) Reference Standard
Supelco
Mebendazole, VETRANAL®, analytical standard
USP
Mebendazole, United States Pharmacopeia (USP) Reference Standard
Mebendazole, European Pharmacopoeia (EP) Reference Standard
Supelco
Mebendazole, analytical standard, ≥98% (HPLC)