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Merck

3D Bioprinting

Illustration showing process of creating human heart layer for layer with bioink using 3D printer

3D bioprinting is a novel technology that enables the generation of precisely controlled 3D tissue constructs with tissue-like complexity. 3D bioprinting is an additive manufacturing process which utilizes 3D printing techniques to build up materials and generate 3D tissue constructs in a layer by layer fashion.  

Bioink, the material used in 3D bioprinting, contains living cells and biomaterials that mimic the extracellular matrix (ECM) environment to support cell adhesion, proliferation, and differentiation after printing. This emerging innovation has the potential to solve many critical unmet needs in medical research, with applications in cosmetics testing, drug discovery, in vitro models, and functional organ replacement.

We offer a comprehensive portfolio of biocompatible fit-for-purpose polymers, water-soluble photoinitiators, and additives specifically for 3D bioprinting and tissue engineering applications. Many of these specialty materials contain moieties that enable easy and fast crosslinking by exposure to UV or visible light, changes in pH, thermal methods like sample warming, or even by exposure to culture media

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Product Features

  • Our wide range of functionalized synthetic polymers with reactive end groups facilitate fabrication of functional hydrogels, even for those with limited chemistry knowledge.
  • Our natural polymers, such as hyaluronic acid, chitosan, gelatin, alginate, and their derivatives, contain cross-linkable functional groups to recapitulate both mechanical and biochemical properties of the native extracellular matrix, and have the necessary surface chemistry for cell attachment, proliferation, and differentiation.
  • Our thermally processable biodegradable polymers, such as polycaprolactones, polylactides and PLGAs, can be used for fabricating rigid structures. These materials have high strength and rigidity and provide structural support for tissue constructs designed to replicate bone.
  • We are continuously adding to our ready-to-use bioinks for extrusion type 3D bioprinting. Our bioinks are based on a variety of biomaterials, including natural polymers, decellularized extracelluar matrix, synthetic polymers and synthetic peptides.

TissueFab® BIOINKS

Our TissueFab® bioinks offer a complete suite of ready-to-use bioink formulations with step-by-step protocols are optimized for high printing fidelity, cell viability, and batch-to-batch reproducibility.


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