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Merck

POLD4

polymerase (DNA-directed), delta 4, accessory subunit

Synonyms:
POLDS, p12
Species:
UniProtKB ID:
Gene ID:
  • Human(57804) Summary: This gene encodes the smallest subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein enhances the activity of DNA polymerase delta and plays a role in fork repair and stabilization through interactions with the DNA helicase Bloom syndrome protein. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]
  • Mouse(69745) polymerase (DNA-directed), delta 4
  • Rat(361698) polymerase (DNA-directed), delta 4, accessory subunit
  • cow(617899) polymerase (DNA-directed), delta 4
  • sheep(101118743) polymerase (DNA-directed), delta 4, accessory subunit
  • domestic guinea pig(100732830) polymerase (DNA-directed), delta 4, accessory subunit
  • naked mole-rat(101706646) polymerase (DNA-directed), delta 4, accessory subunit
  • Thale Cress(837513) DNA polymerase delta subunit 4
  • dog(611847) polymerase (DNA-directed), delta 4, accessory subunit
  • domestic cat(101091308) polymerase (DNA-directed), delta 4, accessory subunit

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-POLD4 antibody produced in mouse, clone 2B11, ascites fluid,
Species Reactivity
human
Application
ELISA
western blot
Monoclonal Anti-POLD4 antibody produced in mouse, clone 2C11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-POLD4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-POLD4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence

Small Molecule - Inhibitor

Product Number
Description
Species
Cytosine β-D-arabinofuranoside hydrochloride, crystalline,
Species
human
Cytarabine, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Cytarabine, United States Pharmacopeia (USP) Reference Standard,
Species
human
Cytarabine, European Pharmacopoeia (EP) Reference Standard,
Species
human
Cytarabine, British Pharmacopoeia (BP) Reference Standard,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human POLD4, AP003419.11,
Species
human